Bradykinin receptor: Difference between revisions

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===Bradykinin B2 receptor===
===Bradykinin B2 receptor===
"A constitutively expressed subtype of bradykinin receptor that may play a role in the acute phase of the inflammatory and pain response. It has high specificity for intact forms of [[bradykinin]] and kallidin. The receptor is coupled to G-Protein, GQ-G11 alpha family and G-Protein, GI-GO alpha family signaling proteins."<ref>{{MeSH|Bradykinin B2 receptor}}</ref>
"A constitutively expressed subtype of bradykinin receptor that may play a role in the acute phase of the inflammatory and [[pain]] response. It has high specificity for intact forms of [[bradykinin]] and kallidin. The receptor is coupled to G-Protein, GQ-G11 alpha family and G-Protein, GI-GO alpha family signaling proteins."<ref>{{MeSH|Bradykinin B2 receptor}}</ref>


==References==
==References==
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<references/>

Revision as of 23:55, 15 June 2008

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Bradykinin receptors are "cell surface receptors that bind bradykinin and related kinins with high affinity and trigger intracellular changes which influence the behavior of cells. The identified receptor types (B-1 and B-2, or BK-1 and BK-2) recognize endogenous kallidin; t-kinins; and certain bradykinin fragments as well as bradykinin itself."[1]

Bradykinin receptors are G-Protein-coupled cell surface receptors.

Classification

Bradykinin B1 receptor

"A subtype of bradykinin receptor that is induced in response to inflammation. It may play a role in chronic inflammation and has a high specificity for kinins lacking the C-terminal arginine such as des-Arg(10)-kallidin and des-Arg(9)-bradykinin. The receptor is coupled to G-Protein, GQ-G11 alpha family and G-Protein, GI-GO alpha family signaling proteins."[2]

Bradykinin B2 receptor

"A constitutively expressed subtype of bradykinin receptor that may play a role in the acute phase of the inflammatory and pain response. It has high specificity for intact forms of bradykinin and kallidin. The receptor is coupled to G-Protein, GQ-G11 alpha family and G-Protein, GI-GO alpha family signaling proteins."[3]

References