Immunosuppressive agents/Definition: Difference between revisions
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Agents that suppress immune function by one of several mechanisms of action. Classical cytotoxic immunosuppressants act by inhibiting DNA synthesis. Others may act through activation of [[T-lymphocyte]]s or by inhibiting the activation of [[T-helper cells | Agents that suppress immune function by one of several mechanisms of action. Classical cytotoxic immunosuppressants act by inhibiting DNA synthesis. Others may act through activation of [[T-lymphocyte]]s or by inhibiting the activation of [[T-helper cells]]. While immunosuppression has been brought about in the past primarily to prevent rejection of transplanted organs, new applications involving mediation of the effects of [[interleukin]]s and other [[cytokines]] are emerging.<noinclude>{{DefMeSH}}</noinclude> | ||
Latest revision as of 23:11, 17 August 2010
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Immunosuppressive agents [r]:
Agents that suppress immune function by one of several mechanisms of action. Classical cytotoxic immunosuppressants act by inhibiting DNA synthesis. Others may act through activation of T-lymphocytes or by inhibiting the activation of T-helper cells. While immunosuppression has been brought about in the past primarily to prevent rejection of transplanted organs, new applications involving mediation of the effects of interleukins and other cytokines are emerging.
This definition is at least in part based on: Anonymous (2024), Immunosuppressive agents (English). Medical Subject Headings. U.S. National Library of Medicine.