User:David E. Volk

The account of this former contributor was not re-activated after the server upgrade of March 2022.

This author is no longer active on the Citizendium

[edit intro]

Dave playing a Michael Kelly Dragonfly acoustic base at the Stingaree Music Festival

 Where David lives it is approximately: 12:37

All truth passes through three stages:

• First, it is ridiculed.
• Second, it is violently opposed.
• Third, it is accepted as being self-evident

Arthur Schopenhauer (1788-1860)

Biography

David E. Volk holds a bachelors degree in mathematics and physics from Minot State (ND) University, and a Ph.D (1995) in physical organic chemistry from North Dakota State University. He completed a post-doctoral fellowship at Duke University Medical Center under Leonard Spicer, was a research scientist at the University of Texas Medical Branch for 12 years, and is currently an Assistant Professor (faculty page) in the Center for Proteomics and Systems Biology at the Brown Foundation Institute for Molecular Medicine, UT Health Science Center Houston.

For much of his career, Dr. Volk's work has used biophysical techniques, such as NMR Spectroscopy and Quantum mechanics, to investigate the structures carcinogen-adducted DNA, proteins and aptamers. Past studies involved solving the structures of the envelope protein domain III of several flaviviruses including West Nile, Yellow fever, Omsk Hemorhaggic Fever and Dengue fever viruses, the S100P protein, glucocorticoid receptor protein, and the VPg protein of poliovirus. Other studies involved both structure and quantum mechanics studies of damaged DNA, such as oxidized DNA or carcinogen-adducted DNA, and DNA aptamers and thioaptamers. His most recent work focuses on metabonomics, proteomics, bioinformatics, and thioaptamer library designs.

Visit his faculty page or publication list for more information.

Chemistry / Health Sciences Articles I Started -part 1

Abacavir Acetaldehyde Acetaminophen Acetic acid Acetone Acid Acyclovir Alanine Aldosterone Amikacin Aminoglycoside Ampicillin Amprenavir Amoxicillin Androstenedione Anion Antiviral drug Arginine Aristolochic acid Arthralgia Arthrodynia Aspartic acid Asparagine Atazanavir (AZT) Atorvastatin (Lipitor) Azathioprine Azlocillin Azole Bioinformatics Boron Boyle's law Carbenicillin Carboxylic acid Carnitine Cefaclor Cefadroxil Cefalotin Cefazolin Cefepime Cerivastatin Chemistry style guide Chorismate Cidofovir Cinoxacin Ciprofloxacin Clofibrate Cloxacillin Colestipol Cortisol Cross product Cysteine Cystine Diazinon DEET Delavirdine Detergent Deuterium Dicloxacillin Didanosine

Econazole Efavirenz Enantiomer Entecavir Eplerenone Ester Estradiol Estrogen Ether Ezetimibe Famciclovir Fenofibrate Folic acid Foscarnet Fosfomycin Flavivirus Flucloxacillin Fluvastatin Fuming sulfuric acid GABA Ganciclovir Gemfibrozil Glucose Glutamic acid Glutamine Hetacillin Hexose Hippurate Histidine Hydrocortisone Hydrophilic HMG CoA Hydrogen/Isotopes Ideal gas law Idoxuridine Indinavir Iron/Isotopes Isoleucine Ketoconazole Lamivudine Leflunomide Leucine Lewis acid Lewis acid-base theory List of NMR experiments Lovastatin Lysine Mesalamine Methionine Methotrexate Mevalonate Mevastatin Mezlocillin Midodrine Minocycline NADPH

Chemistry / Health Sciences Articles I Started -part 2

Nelfinavir Netilmicin Nitroglycerin Nitromethane Neuralgia Oseltamivir Oxacillin NMR active elements Penciclovir Penicillin G Penicillin V Phenylalanine Phosphate Phosphoric acid Phosphorus Piperacillin Pravastatin Prednisone Prednisolone Progesterone Proline Protease inhibitor Protein structure Rhabdomyolysis Ribavirin Rimantadine Ritonavir Rosuvastatin (Crestor) Saquinavir Serine Simvastatin Spironolactone Stavudine Stent Steroid Streptomycin Sulfasalazine Sulfur dioxide Sulfuric acid Tenofovir Testosterone Thioaptamer Tioconazole Tipranavir Threonine Triazole Tryptophan Tyrosine Valine Vidarabine Voriconazole Warfarin West Nile virus Zalcitabine Zanamivir Zidovudine

Music Articles I Created

1. Band of Heathens
2. Cover band
3. Eliza Gilkyson
4. Gurf Morlix
5. Lightnin' Hopkins
6. Liz and Lincoln
7. Lucinda Williams
8. Rex Bell
9. Rex Bell/Discography
10. REO Speedwagon
11. REO Speedwagon/Discography
12. Rush
13. Singer-songwriter
14. Hayes Carll
15. Scott Nolan
16. Stingaree Music Festival cluster
17. Townes Van Zandt
18. Townes Van Zandt/Discography (this was work!)

Other Articles I Created

1. Carne gasada - a savory Mexican stew
2. Chateau de Mores
3. Chili-mac (vegetarian)
4. Enchilada sauce - both red and green
5. Galveston County Daily News
6. Kim Komando
7. Kirchhoff's current law
8. Kirchhoff's voltage law
9. Law of cosines
10. Law of sines
11. Judge Susan Criss of Galveston, County, Texas
12. Texas Hold 'Em

Areas of Expertise

1. Nuclear Magnetic Resonance (NMR) spectroscopy
   1. Protein NMR Structures
      1. West Nile virus ED3
      2. Omsk Hemorhagic fever ED3
      3. Dengue 4 virus
      4. Yellow fever virus
   2. DNA Structures
      1. Benzo[a]pyrene-adducted (carcinogenic) DNA
      2. Oxidatively Damaged DNA
      3. Thioaptamer DNA
   3. Metabonomics/Metabolomics
2. Quantum Mechanics
   1. DNA:DNA Interactions
   2. DNA:Metal Interactions
3. Lewis Acid Chemistry
   1. AlCl3 and Et2AlCl mediated ring opening reactions
   2. SnCl4 mediated ring opening reactions
4. Protein Expression & Purification
5. Molecular Mechanics

Areas of General Competence

• Physical/Organic Chemistry
• Molecular Biology
• Structural Biology
• Physics
• Mathematics
• Computer Programming
  • Pascal
  • Perl
  • C++
• MAcromolecular Purification Methods
• Surface Plasmon Resonance (Biacore)
• Binding thermodynamics and kinetics

Hobbies

• Bass Guitar
• Texas Holdem'
• Bird Watching

• CZ:Biochemistry Subgroup