Fludarabine: Difference between revisions
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imported>David E. Volk (Adding structure of fludarabine, a AMP analog) |
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{{Image|Fludarabine phosphate.png|right|150px|Fludarabine monophosphate, an analog of adenosine.}} | {{Image|Fludarabine phosphate.png|right|150px|Fludarabine monophosphate, an analog of adenosine.}} | ||
In [[medicine]], [[fludarabine]] is a [[medication]] that is a [[antineoplastic agent]]. It is approved by the U.S. Food and Drug Administration for the palliative treatment [[chronic lymphocytic leukemia]] (CLL). It is structurally related to the naturally | In [[medicine]], [[fludarabine]] is a [[medication]] that is a [[antineoplastic agent]]. It is approved by the U.S. Food and Drug Administration for the palliative treatment [[chronic lymphocytic leukemia]] (CLL). It is structurally related to the naturally occurring base [[adenosine]]-monophosphate used in both [[DNA]] and [[RNA]], but it contains a [[fluorine]] atom and the geometry of the [[ribose]] ring at position 2' is reversed from that of normal DNA. | ||
==References== | ==References== | ||
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==External links== | ==External links== | ||
{{CZMed}} | {{CZMed}}[[Category:Suggestion Bot Tag]] | ||
Latest revision as of 11:03, 17 August 2024
In medicine, fludarabine is a medication that is a antineoplastic agent. It is approved by the U.S. Food and Drug Administration for the palliative treatment chronic lymphocytic leukemia (CLL). It is structurally related to the naturally occurring base adenosine-monophosphate used in both DNA and RNA, but it contains a fluorine atom and the geometry of the ribose ring at position 2' is reversed from that of normal DNA.
References
External links
The most up-to-date information about Fludarabine and other drugs can be found at the following sites.
- Fludarabine - FDA approved drug information (drug label) from DailyMed (U.S. National Library of Medicine).
- Fludarabine - Drug information for consumers from MedlinePlus (U.S. National Library of Medicine).
- Fludarabine - Detailed information from DrugBank.