Insulin-secreting cell: Difference between revisions

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(New page: In medicine, '''insulin resistance''' is "diminished effectiveness of insulin in lowering blood sugar levels: requiring the use of 200 units or more of insulin per day to prevent h...)
 
imported>Meg Taylor
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In [[medicine]], '''insulin resistance''' is "diminished effectiveness of [[insulin]] in lowering blood sugar levels: requiring the use of 200 units or more of insulin per day to prevent hyperglycemia or ketosis. Tt can be caused by the presence of insulin antibodies or the abnormalities in insulin receptors (receptor, insulin) on target cell surfaces. It is often associated with [[obesity]]; [[diabetic ketoacidosis]]; [[infection]]; and certain rare conditions."<ref>{{MeSH}}</ref>
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In [[medicine]] and [[physiology]], '''insulin-secreting cells''', also called '''pancreatic beta cells''', are a "type of pancreatic cell representing about 50-80% of the islet cells. Beta cells secrete [[insulin]]."<ref>{{MeSH}}</ref>
 
[[insulin-secreting cell|Beta cell]] function (HOMA-B) can be measured by:<ref name="pmid3899825">{{cite journal |author=Matthews DR, Hosker JP, Rudenski AS, Naylor BA, Treacher DF, Turner RC |title=Homeostasis model assessment: insulin resistance and beta-cell function from fasting plasma glucose and insulin concentrations in man |journal=Diabetologia |volume=28 |issue=7 |pages=412–9 |year=1985 |month=July |pmid=3899825 |doi= |url= |issn=}}</ref>
:<math>\text{HOMA-B} = \frac{20 * \text{fasting insulin}}{\text{fasting plasma glucose} - 3.5}</math>


==References==
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Latest revision as of 08:13, 30 September 2009

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In medicine and physiology, insulin-secreting cells, also called pancreatic beta cells, are a "type of pancreatic cell representing about 50-80% of the islet cells. Beta cells secrete insulin."[1]

Beta cell function (HOMA-B) can be measured by:[2]

References

  1. Anonymous (2024), Insulin-secreting cell (English). Medical Subject Headings. U.S. National Library of Medicine.
  2. Matthews DR, Hosker JP, Rudenski AS, Naylor BA, Treacher DF, Turner RC (July 1985). "Homeostasis model assessment: insulin resistance and beta-cell function from fasting plasma glucose and insulin concentrations in man". Diabetologia 28 (7): 412–9. PMID 3899825[e]