Cefoxitin: Difference between revisions
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Latest revision as of 06:00, 26 July 2024
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| cefoxitin | |||||||
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| Uses: | antibiotic drug | ||||||
| Properties: | beta-lactam | ||||||
| Hazards: | see drug interactions | ||||||
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Cefoxitin is a semi-synthetic, broad-spectrum cephalosporin type of antibiotic, derived from cephamycin C produced by Streptmyces lactamdurans. It is administered intravenously. It is sold under the brand names Mefoxin and Mefoxitin.
Mechanism of Action
Cephalosporin and penicilin-based antbacterial agents inhibit cell wall synthesis of bacteria by binding to penicilin-binding proteins in bacteria through an acylation reaction of the core beta-lactam structure with the cell's proteins.
Chemistry
The IUPAC name for cefoxitin is (6R,7S)-3-(carbamoyloxymethyl)-7-methoxy-8-oxo-7-[(2-thiophen-2-ylacetyl)amino]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid. It has chemical formula C16H17N3O7S2 and molecular mass of 427.4520 grams/mol. Its antibiotic properties are due to its core beta-lactam structure, which is common to all cephalosporins.
References
The most up-to-date information about Cefoxitin and other drugs can be found at the following sites.
- Cefoxitin - FDA approved drug information (drug label) from DailyMed (U.S. National Library of Medicine).
- Cefoxitin - Drug information for consumers from MedlinePlus (U.S. National Library of Medicine).
- Cefoxitin - Detailed information from DrugBank.