Talk:Neurotransmitter: Difference between revisions

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|                  by = [[User:Petréa Mitchell|Petréa Mitchell]] 11:01, 8 April 2007 (CDT)
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I'd favour treating peptides separately for several reasons
I'd favour treating peptides separately for several reasons

Revision as of 01:39, 11 November 2007

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 Definition:  A class of chemicals which relay, amplify or modulate electrical signals between a neuron and other cells in the nervous system. [d] [e]
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I'd favour treating peptides separately for several reasons 1) there are so many of them - think more than 100 now recognised as neuronal messengers

2) they seem to be universal, been suggested that every neurone also makes one or more peptide messenger

3) peptides seem to be always co expressed with a conventional neurotransmitter

4) peptides are in large dense cored vesicles not in small synaptic vesicles, and these are not conspicuously targeted to nerve endings, so are probably not particularly released synaptically

I think therefore that what is generally true of conventional neurotransmitters is not generally true of peptide messengers. There are some possible exceptions of peptides that do look like conventional transmitters (Substance P) but I think these are exceptions.

So I suggest this article is better focussed on the conventional transmitters and peptides treated separately?Gareth Leng 08:34, 11 February 2007 (CST)

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