Systemic lupus erythematosus: Difference between revisions
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==Diagnosis== | ==Diagnosis== | ||
[[Image:SLE-alternative criteria.jpg|thumb|right|250px|{{#ifexist:Template:SLE-alternative criteria.jpg/credit|{{SLE-alternative criteria.jpg/credit}}<br/>|}}Alternate criteria<ref name="pmid3060613">{{cite journal |author=Edworthy SM, Zatarain E, McShane DJ, Bloch DA |title=Analysis of the 1982 ARA lupus criteria data set by recursive partitioning methodology: new insights into the relative merit of individual criteria |journal=J. Rheumatol. |volume=15 |issue=10 |pages=1493-8 |year=1988 |pmid=3060613 |doi=}}</ref>]] | [[Image:SLE-alternative criteria.jpg|thumb|right|250px|{{#ifexist:Template:SLE-alternative criteria.jpg/credit|{{SLE-alternative criteria.jpg/credit}}<br/>|}}Alternate criteria<ref name="pmid3060613">{{cite journal |author=Edworthy SM, Zatarain E, McShane DJ, Bloch DA |title=Analysis of the 1982 ARA lupus criteria data set by recursive partitioning methodology: new insights into the relative merit of individual criteria |journal=J. Rheumatol. |volume=15 |issue=10 |pages=1493-8 |year=1988 |pmid=3060613 |doi=}}</ref>]] | ||
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==References== | ==References== | ||
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Revision as of 23:30, 22 December 2007
Diagnosis
Alternative criteria
Recursive partitioning has been used to identify more parsimonious criteria. [1] This analysis presented two diagnostic classification trees:
1. Simplest classification tree: LSE is diagnosed if the patient has an immunologic disorder (anti-DNA antibody, anti-Smith antibody, false positive syphilis test, or LE cells) or malar rash.
- sensitivity = 92%
- specificity = 92%
2. Full classification tree: Uses 6 criteria.
- sensitivity = 97%
- specificity = 95%
Other alternative criteria have been suggested.[2]
References
- ↑ 1.0 1.1 Edworthy SM, Zatarain E, McShane DJ, Bloch DA (1988). "Analysis of the 1982 ARA lupus criteria data set by recursive partitioning methodology: new insights into the relative merit of individual criteria". J. Rheumatol. 15 (10): 1493-8. PMID 3060613. [e]
- ↑ Hughes GR (1998). "Is it lupus? The St. Thomas' Hospital "alternative" criteria". Clin. Exp. Rheumatol. 16 (3): 250-2. PMID 9631744. [e]