Platelet aggregation inhibitors: Difference between revisions

From Citizendium
Jump to navigation Jump to search
imported>Robert Badgett
No edit summary
imported>Robert Badgett
Line 13: Line 13:


===Thienopyridines===
===Thienopyridines===
[[Thienopyridines]] include [[clopidogrel]] and [[ticlopidine]].
[[Thienopyridines]] include [[clopidogrel]], [[ticlopidine]], and the prodrug [[prasugrel]].


==References==
==References==
<references/>
<references/>

Revision as of 20:53, 21 October 2009

This article is a stub and thus not approved.
Main Article
Discussion
Related Articles  [?]
Bibliography  [?]
External Links  [?]
Citable Version  [?]
 
This editable Main Article is under development and subject to a disclaimer.

Platelet aggregation inhibitors, also called antiplatelet drugs, are "drugs or agents which antagonize or impair any mechanism leading to blood platelet aggregation, whether during the phases of activation and shape change or following the dense-granule release reaction and stimulation of the prostaglandin-thromboxane system."[1]

Classification

Adenosine diphosphate (ADP) blocker

This includes dipyrimadole.

Cyclooxygenase-1 blockers

Cyclooxygenase-1 blockers include aspirin.

Glycoprotein IIb/IIIa inhibitors

Inhibitors of the platelet glycoprotein GPIIb-IIIa complex include eptifibatide, tirofiban, and the monoclonal antibody abciximab.

Thienopyridines

Thienopyridines include clopidogrel, ticlopidine, and the prodrug prasugrel.

References