Acebutolol: Difference between revisions

From Citizendium
Jump to navigation Jump to search
imported>David E. Volk
No edit summary
imported>David E. Volk
Line 19: Line 19:
== References ==
== References ==
<references/>
<references/>
== General References ==
{{CZMed}}

Revision as of 13:53, 4 July 2009

This article is developing and not approved.
Main Article
Discussion
Related Articles  [?]
Bibliography  [?]
External Links  [?]
Citable Version  [?]
 
This editable Main Article is under development and subject to a disclaimer.
Acebutolol.png
acebutolol
IUPAC name: see chemistry section
Synonyms: dl-acebutolol
Formula: C18H28N2O4

 Uses: hypertention;angina pectoris

 Properties:

 Hazards:

Mass (g/mol): CAS #:
336.4259 37517-30-9


Acebutolol is a cardioselective, beta-adrenergic antagonist (beta blocker) with relatively little effects, at low dosage, on bronchial receptors compared to other beta-blockers such as atenolol and propranolol. Epinephrine typically binds to these same receptors, subsequently raising heart rate and blood pressure, but this action is blocked when beta-blockers such as acebutolol bind to these receptors, thereby interferring with epinephrine binding. Blood pressure is also increased by the release of renin, a hormone produced in the kidneys, which narrows blood vessels. By preventing renin release, acebutolol reduces blood pressure by a second mechanism. [1]

References

General References

The most up-to-date information about Acebutolol and other drugs can be found at the following sites.