Cytochrome P-450 CYP2D6: Difference between revisions

Revision as of 11:49, 29 August 2009

Crystal Structure of Human Cytochrome P450 2d6.

In biology, the cytochrome P-450 CYP2D6 is a "cytochrome P-450 enzyme that catalyzes the hydroxylation of many drugs and environmental chemicals, such as debrisoquine; adrenergic receptor antagonists; and tricyclic antidepressants. This enzyme is deficient in up to 10 percent of the Caucasian population."^[1]

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+{{Image|Mmdbimage-36878.png|right|350px|Crystal Structure of Human Cytochrome P450 2d6.}}
 In [[biology]], the '''cytochrome P-450 CYP2D6''' is a "[[cytochrome P-450]] enzyme that catalyzes the hydroxylation of many drugs and environmental chemicals, such as debrisoquine; [[Adrenergic beta-antagonist|adrenergic receptor antagonist]]s; and [[tricyclic antidepressant]]s. This enzyme is deficient in up to 10 percent of the Caucasian population."<ref>{{MeSH}}</ref>
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 * [http://www.ncbi.nlm.nih.gov/sites/entrez?db=nuccore Entrez Nucleotide]: [http://www.ncbi.nlm.nih.gov/nuccore/68509919 68509919]; [[PubMed]] [http://www.ncbi.nlm.nih.gov/sites/entrez?db=pubmed&cmd=link&linkname=nuccore_pubmed_weighted&uid=68509919 search]
 * [http://www.ncbi.nlm.nih.gov/sites/entrez?db=Protein Entrez Protein]: [http://www.ncbi.nlm.nih.gov/protein/40805836 40805836]; [[PubMed]] [http://www.ncbi.nlm.nih.gov/sites/entrez?db=pubmed&cmd=link&linkname=protein_pubmed_weighted&uid=40805836 search]
+* [http://www.ncbi.nlm.nih.gov/sites/entrez?db=Structure Entrez Structure]: [http://www.ncbi.nlm.nih.gov/sites/entrez?SUBMIT=y&db=structure&orig_db=structure&term=2F9Q 2F9Q]
 ==References==
 <references/>