Darusentan: Difference between revisions

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Revision as of 07:59, 19 September 2009

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Darusentan.png
darusentan
IUPAC name: (2S)-2-(4,6-dimethoxypyrimidin-2-yl)oxy-3-methoxy-3,3-diphenylpropanoic

acid

Synonyms:
Formula: C22H22N2O6
 Uses: hypertension
 Properties:
 Hazards: see side effects & drug interactions
Mass (g/mol): CAS #:
410.41988 171714-84-4


In medicine, darusentan is a medication for treating hypertension that is a selective endothelin type A antagonist. It is a vasodilator.[1]

Drug toxicity

Fluid retention is the most common drug toxicity.[1]

References

  1. ↑ 1.0 1.1 Weber MA et al. (2009) A selective endothelin-receptor antagonist to reduce blood pressure in patients with treatment-resistant hypertension: a randomised, double-blind, placebo-controlled trial. Lancet DOI:10.1016/S0140-6736(09)61500-2
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