Peptidyl-dipeptidase A: Difference between revisions
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imported>Robert Badgett (New page: {{subpages}} '''Peptidyl-dipeptidase A''' is "peptidyl-dipeptidase that catalyzes the release of a C-terminal dipeptide, -Xaa-*-Xbb-Xcc, when neither Xaa nor Xbb is Pro. It is a Cl(-)-depe...) |
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'''Peptidyl-dipeptidase A''' is "peptidyl-dipeptidase that catalyzes the release of a C-terminal dipeptide, -Xaa-*-Xbb-Xcc, when neither Xaa nor Xbb is Pro. It is a Cl(-)-dependent, zinc glycoprotein that is generally membrane-bound and active at neutral pH. It may also have endopeptidase activity on some substrates".<ref>{{MeSH}}</ref> | '''Peptidyl-dipeptidase A''' is a "peptidyl-dipeptidase that catalyzes the release of a C-terminal dipeptide, -Xaa-*-Xbb-Xcc, when neither Xaa nor Xbb is Pro. It is a Cl(-)-dependent, zinc glycoprotein that is generally membrane-bound and active at neutral pH. It may also have endopeptidase activity on some substrates".<ref>{{MeSH}}</ref> | ||
Peptidyl-dipeptidase A is also called '''Angiotensin I converting enzyme''' or '''Angiotensin converting enzyme''' converts [[angiotensin]] I to [[angiotensin]] II in the [[renin-angiotensin system]]. | Peptidyl-dipeptidase A is also called '''Angiotensin I converting enzyme''' or '''Angiotensin converting enzyme''' converts [[angiotensin]] I to [[angiotensin]] II in the [[renin-angiotensin system]]. | ||
Revision as of 00:40, 16 June 2008
Peptidyl-dipeptidase A is a "peptidyl-dipeptidase that catalyzes the release of a C-terminal dipeptide, -Xaa-*-Xbb-Xcc, when neither Xaa nor Xbb is Pro. It is a Cl(-)-dependent, zinc glycoprotein that is generally membrane-bound and active at neutral pH. It may also have endopeptidase activity on some substrates".[1]
Peptidyl-dipeptidase A is also called Angiotensin I converting enzyme or Angiotensin converting enzyme converts angiotensin I to angiotensin II in the renin-angiotensin system.
Peptidyl-dipeptidase A is also called Kininase II because it inactivates bradykinin in the kallikrein-kinin system.
References
- ↑ Anonymous (2024), Peptidyl-dipeptidase A (English). Medical Subject Headings. U.S. National Library of Medicine.