Transfusion reaction: Difference between revisions
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===Hemolytic reactions=== | ===Hemolytic reactions=== | ||
==== | Hemolytic reactions due to [[blood group incompatibility]] is "mismatch between donor and recipient blood. [[Antibody|Antibodies]] present in the recipient's serum are directed against [[antigen]]s in the donor product. Such a mismatch may result in a transfusion reaction in which, for example, donor blood is hemolyzed."<ref>{{MeSH|Blood group incompatibility}}</ref> | ||
====Acute hemolytic transfusion reactions==== | |||
ICD9: {{ICD9|999.6}} | ICD9: {{ICD9|999.6}} | ||
'''Acute hemolytic transfusion reactions''' due to ABO incompatibility. | |||
==== | ====Delayed hemolytic transfusion reactions==== | ||
ICD9: {{ICD9|999.7}} | ICD9: {{ICD9|999.7}} | ||
This reaction usually causes delayed hemolysis. | This reaction usually causes delayed hemolysis. This may be caused by Rh incompatibility. | ||
====Transfusion related acute lung injury (TRALI)==== | ====Transfusion related acute lung injury (TRALI)==== | ||
Revision as of 18:37, 6 November 2008
A classification has been proposed by the American Association of Blood Banks (AABB).[1] In addition, the classification below is based on ICD9.
Immunologic
Febrile, nonhemolytic transfusion reaction (FNHTR)
This is a minor, acute reaction suggested by negative a Coombs' test, no free hemoglobin in the plasma, and no hemoglobin in the urine.
Hemolytic reactions
Hemolytic reactions due to blood group incompatibility is "mismatch between donor and recipient blood. Antibodies present in the recipient's serum are directed against antigens in the donor product. Such a mismatch may result in a transfusion reaction in which, for example, donor blood is hemolyzed."[2]
Acute hemolytic transfusion reactions
ICD9: 999.6
Acute hemolytic transfusion reactions due to ABO incompatibility.
Delayed hemolytic transfusion reactions
ICD9: 999.7
This reaction usually causes delayed hemolysis. This may be caused by Rh incompatibility.
ICD9: 518.7
This is an acute reaction.
Nonimmunologic
Chemical reactions
- Hemosiderosis
- Hypocalcemia from citrate toxicity
- Hyperkalemia
- Metabolic alkalosis and hypokalemia due to citrate
Transmission of infection
Other reactions
- Hypothermia
- Circulatory overload
- Hypotension associated with leukoreduced blood
- Transfusion-related acute lung injury (pulmonary leukoagglutinin reaction) (TRALI)
References
- ↑ Sanders RP, Geiger TL, Heddle N, Pui CH, Howard SC (April 2007). "A revised classification scheme for acute transfusion reactions". Transfusion 47 (4): 621–8. DOI:10.1111/j.1537-2995.2007.01163.x. PMID 17381620. Research Blogging.
- ↑ Anonymous (2024), Blood group incompatibility (English). Medical Subject Headings. U.S. National Library of Medicine.