Fludarabine: Difference between revisions

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Fludarabine monophosphate, an analog of adenosine.

In medicine, fludarabine is a medication that is a antineoplastic agent. It is approved by the U.S. Food and Drug Administration for the palliative treatment chronic lymphocytic leukemia (CLL). It is structurally related to the naturally occurring base adenosine-monophosphate used in both DNA and RNA, but it contains a fluorine atom and the geometry of the ribose ring at position 2' is reversed from that of normal DNA.

The most up-to-date information about Fludarabine and other drugs can be found at the following sites.

Fludarabine - FDA approved drug information (drug label) from DailyMed (U.S. National Library of Medicine).
Fludarabine - Drug information for consumers from MedlinePlus (U.S. National Library of Medicine).
Fludarabine - Detailed information from DrugBank.

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-In [[medicine]], [[fludarabine]] is a [[medication]] that is a  [[antineoplastic agent]]. It is approved by the U.S. Food and Drug Administration for the palliative treatment [[chronic lymphocytic leukemia]] (CLL).  It is structurally related to the naturally occuring base [[adenosine]]-monophosphate used in both [[DNA]] and [[RNA]], but it contains a [[fluorine]] atom and the geometry of the [[ribose]] ring at position 2' is reversed from that of normal DNA.
+In [[medicine]], [[fludarabine]] is a [[medication]] that is a  [[antineoplastic agent]]. It is approved by the U.S. Food and Drug Administration for the palliative treatment [[chronic lymphocytic leukemia]] (CLL).  It is structurally related to the naturally occurring base [[adenosine]]-monophosphate used in both [[DNA]] and [[RNA]], but it contains a [[fluorine]] atom and the geometry of the [[ribose]] ring at position 2' is reversed from that of normal DNA.
 ==References==