Fludarabine: Difference between revisions

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imported>Howard C. Berkowitz
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imported>David E. Volk
(Adding structure of fludarabine, a AMP analog)
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In [[medicine]], [[fludarabine]] is a [[medication]] that is a  [[antineoplastic agent]]. It is approved by the U.S. Food and Drug Administration for the palliative treatment [[chronic lymphocytic leukemia]] (CLL).
{{Image|Fludarabine phosphate.png|right|150px|Fludarabine monophosphate, an analog of adenosine.}}
In [[medicine]], [[fludarabine]] is a [[medication]] that is a  [[antineoplastic agent]]. It is approved by the U.S. Food and Drug Administration for the palliative treatment [[chronic lymphocytic leukemia]] (CLL).  It is structurally related to the naturally occuring base [[adenosine]]-monophosphate used in both [[DNA]] and [[RNA]], but it contains a [[fluorine]] atom and the geometry of the [[ribose]] ring at position 2' is reversed from that of normal DNA.


==References==  
==References==  

Revision as of 14:57, 10 May 2009

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(CC) Image: David E. Volk
Fludarabine monophosphate, an analog of adenosine.

In medicine, fludarabine is a medication that is a antineoplastic agent. It is approved by the U.S. Food and Drug Administration for the palliative treatment chronic lymphocytic leukemia (CLL). It is structurally related to the naturally occuring base adenosine-monophosphate used in both DNA and RNA, but it contains a fluorine atom and the geometry of the ribose ring at position 2' is reversed from that of normal DNA.

References


External links

The most up-to-date information about Fludarabine and other drugs can be found at the following sites.