Acebutolol: Difference between revisions

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'''Acebutolol''' is a cardioselective, [[beta-adrenergic antagonist]] (beta blocker) with relatively little effects, at low dosage, on bronchial receptors compared to other beta-blockers such as [[atenolol]] and [[propranolol]]. [[Epinephrine]] typically binds to these same receptors, subsequently raising heart rate and blood pressure, but this action is blocked when beta-blockers such as acebutolol bind to these receptors, thereby interferring with epinephrine binding.  Blood pressure is also increased by the release of [[renin]], a [[hormone]] produced in the kidneys, which narrows blood vessels.  By preventing renin release, acebutolol reduces blood pressure by a second mechanism.[http://www.drugbank.ca/drugs/DB01193 Acebutolol at DrugBank]
'''Acebutolol''' is a cardioselective, [[beta-adrenergic antagonist]] (beta blocker) with relatively little effects, at low dosage, on bronchial receptors compared to other beta-blockers such as [[atenolol]] and [[propranolol]]. [[Epinephrine]] typically binds to these same receptors, subsequently raising heart rate and blood pressure, but this action is blocked when beta-blockers such as acebutolol bind to these receptors, thereby interferring with epinephrine binding.  Blood pressure is also increased by the release of [[renin]], a [[hormone]] produced in the kidneys, which narrows blood vessels.  By preventing renin release, acebutolol reduces blood pressure by a second mechanism. <ref>[http://www.drugbank.ca/drugs/DB01193 Acebutolol at DrugBank]</ref>


== References ==
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Revision as of 13:53, 4 July 2009

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Acebutolol.png
acebutolol
IUPAC name: see chemistry section
Synonyms: dl-acebutolol
Formula: C18H28N2O4

 Uses: hypertention;angina pectoris

 Properties:

 Hazards:

Mass (g/mol): CAS #:
336.4259 37517-30-9


Acebutolol is a cardioselective, beta-adrenergic antagonist (beta blocker) with relatively little effects, at low dosage, on bronchial receptors compared to other beta-blockers such as atenolol and propranolol. Epinephrine typically binds to these same receptors, subsequently raising heart rate and blood pressure, but this action is blocked when beta-blockers such as acebutolol bind to these receptors, thereby interferring with epinephrine binding. Blood pressure is also increased by the release of renin, a hormone produced in the kidneys, which narrows blood vessels. By preventing renin release, acebutolol reduces blood pressure by a second mechanism. [1]

References