Propranolol: Difference between revisions

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imported>Robert Badgett
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imported>Robert Badgett
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==Metabolism==
==Metabolism==
Propranolol is metabolized in the liver by several isoenzymes of [[cytochrome P-450]]  [http://www.ncbi.nlm.nih.gov/sites/entrez/?db=gene&cmd=Retrieve&dopt=summary&list_uids=1565 2D6].
Propranolol is metabolized in the liver by several isoenzymes of [[cytochrome P-450]].


==External links==
==External links==

Revision as of 21:47, 14 July 2009

Propranolol.png
propranolol
IUPAC name:
Synonyms:
Formula:

 Uses: hypertention;angina pectoris

 Properties: lipophilic

 Hazards: see side effects & drug interactions

Mass (g/mol): CAS #:


In medicine, propranolol is "a widely used non-cardioselective beta-adrenergic antagonist. Propranolol has been used for myocardial infarction; arrhythmia; angina pectoris; hypertension; hyperthyroidism; migraine; pheochromocytoma; and anxiety but adverse effects instigate replacement by newer drugs."[1]

History

Propranolol was developed by Akrimax Pharms. Atenolol received approval in the United States November 13, 1967.[2]

Generic propranolol was available October 22, 1985.[3]

Metabolism

Propranolol is metabolized in the liver by several isoenzymes of cytochrome P-450.

External links

The most up-to-date information about Propranolol and other drugs can be found at the following sites.


References

  1. Anonymous (2024), Propranolol (English). Medical Subject Headings. U.S. National Library of Medicine.
  2. Drugs@FDA. U S Food and Drug Administration
  3. Drugs@FDA. U S Food and Drug Administration