Leucovorin rescue: Difference between revisions
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'''Leucovorin rescue''' is a type of [[cancer]] chemotherapy, sometimes called effective [[heroic medicine]], in which a lethal dose of [[methotrexate]] is administered, and then an antidote, [[leucovorin]], given at a delayed time calculated to kill a maximum number of malignant cells without killing the patient.<ref>{{citation | |||
| title = Optimization of High-Dose Methotrexate with Leucovorin Rescue Therapy in the L1210 Leukemia and Sarcoma 180 Murine Tumor Models1 | |||
| author = Sirotnak FM, Moccio DM, Dorick DM | |||
| journal = Cancer Research | |||
| url = http://cancerres.aacrjournals.org/content/38/2/345.short | |||
| date = February 1978 | volume =38 | page= 345 | |||
}}</ref> | |||
==References== | |||
{{reflist}} | |||
Revision as of 17:00, 7 October 2010
Leucovorin rescue is a type of cancer chemotherapy, sometimes called effective heroic medicine, in which a lethal dose of methotrexate is administered, and then an antidote, leucovorin, given at a delayed time calculated to kill a maximum number of malignant cells without killing the patient.[1]
References
- ↑ Sirotnak FM, Moccio DM, Dorick DM (February 1978), "Optimization of High-Dose Methotrexate with Leucovorin Rescue Therapy in the L1210 Leukemia and Sarcoma 180 Murine Tumor Models1", Cancer Research 38: 345