HDL cholesterol: Difference between revisions

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It is not clear whether insufficient HDL causes [[coronary artery disease]]<ref name="pmid22607825">{{cite journal| author=Voight BF, Peloso GM, Orho-Melander M, Frikke-Schmidt R, Barbalic M, Jensen MK et al.| title=Plasma HDL cholesterol and risk of myocardial infarction: a mendelian randomisation study. | journal=Lancet | year= 2012 | volume=  | issue=  | pages=  | pmid=22607825 | doi=10.1016/S0140-6736(12)60312-2 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=22607825  }} </ref> and raising the HDL does not seem to reduce [[coronary artery disease]].<ref name="pmid22085343">{{cite journal| author=AIM-HIGH Investigators. Boden WE, Probstfield JL, Anderson T, Chaitman BR, Desvignes-Nickens P et al.| title=Niacin in patients with low HDL cholesterol levels receiving intensive statin therapy. | journal=N Engl J Med | year= 2011 | volume= 365 | issue= 24 | pages= 2255-67 | pmid=22085343 | doi=10.1056/NEJMoa1107579 | pmc= | url= }} </ref>
It is not clear whether insufficient HDL causes [[coronary artery disease]]<ref name="pmid22607825">{{cite journal| author=Voight BF, Peloso GM, Orho-Melander M, Frikke-Schmidt R, Barbalic M, Jensen MK et al.| title=Plasma HDL cholesterol and risk of myocardial infarction: a mendelian randomisation study. | journal=Lancet | year= 2012 | volume=  | issue=  | pages=  | pmid=22607825 | doi=10.1016/S0140-6736(12)60312-2 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=22607825  }} </ref> and raising the HDL does not seem to reduce [[coronary artery disease]].<ref name="pmid22085343">{{cite journal| author=AIM-HIGH Investigators. Boden WE, Probstfield JL, Anderson T, Chaitman BR, Desvignes-Nickens P et al.| title=Niacin in patients with low HDL cholesterol levels receiving intensive statin therapy. | journal=N Engl J Med | year= 2011 | volume= 365 | issue= 24 | pages= 2255-67 | pmid=22085343 | doi=10.1056/NEJMoa1107579 | pmc= | url= }} </ref>
Low HDL is part of [[hypoalphalipoproteinemia]].


==References==
==References==
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Revision as of 13:42, 31 January 2013

In physiology, HDL cholesterol (HDL) is "cholesterol which is contained in or bound to high-density lipoproteins (HDL), including cholesterol esters and free cholesterol."[1]

It is not clear whether insufficient HDL causes coronary artery disease[2] and raising the HDL does not seem to reduce coronary artery disease.[3]

Low HDL is part of hypoalphalipoproteinemia.

References

  1. Anonymous (2024), HDL cholesterol (English). Medical Subject Headings. U.S. National Library of Medicine.
  2. Voight BF, Peloso GM, Orho-Melander M, Frikke-Schmidt R, Barbalic M, Jensen MK et al. (2012). "Plasma HDL cholesterol and risk of myocardial infarction: a mendelian randomisation study.". Lancet. DOI:10.1016/S0140-6736(12)60312-2. PMID 22607825. Research Blogging.
  3. AIM-HIGH Investigators. Boden WE, Probstfield JL, Anderson T, Chaitman BR, Desvignes-Nickens P et al. (2011). "Niacin in patients with low HDL cholesterol levels receiving intensive statin therapy.". N Engl J Med 365 (24): 2255-67. DOI:10.1056/NEJMoa1107579. PMID 22085343. Research Blogging.