Talk:Neurotransmitter

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Revision as of 10:01, 8 April 2007 by imported>Petréa Mitchell (Article checklist)
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Article Checklist for "Neurotransmitter"
Workgroup category or categories Health Sciences Workgroup, Biology Workgroup, Chemistry Workgroup [Editors asked to check categories]
Article status External article: from another source, with little change
Underlinked article? Yes
Basic cleanup done? Yes
Checklist last edited by Petréa Mitchell 11:01, 8 April 2007 (CDT)

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I'd favour treating peptides separately for several reasons 1) there are so many of them - think more than 100 now recognised as neuronal messengers

2) they seem to be universal, been suggested that every neurone also makes one or more peptide messenger

3) peptides seem to be always co expressed with a conventional neurotransmitter

4) peptides are in large dense cored vesicles not in small synaptic vesicles, and these are not conspicuously targeted to nerve endings, so are probably not particularly released synaptically

I think therefore that what is generally true of conventional neurotransmitters is not generally true of peptide messengers. There are some possible exceptions of peptides that do look like conventional transmitters (Substance P) but I think these are exceptions.

So I suggest this article is better focussed on the conventional transmitters and peptides treated separately?Gareth Leng 08:34, 11 February 2007 (CST)