Uremia
Uremia is defined as "the illness accompanying kidney failure that cannot be explained by derangements in extracellular volume, inorganic ion concentrations, or lack of known renal synthetic products."[1]
Signs and symptoms
Signs such as well-being, fatigue, and reduced stamina may occur when the glomerular filtration rate falls below 50 to 60 ml per minute per 1.73 m2.[1]
Subtle cognitive dysfunction may occur when the glomerular filtration rate falls below 30 to 60 ml per minute per 1.73 m2.[1]
INsulin resistance may occur when the glomerular filtration rate falls below 50 ml per minute per 1.73 m2.[1]
Treatment
Treatment options include hemodialysis, peritoneal dialysis, or renal transplant. Hemodialysis is usually done three times a week and each session removes about tho-thirds of the total-body urea content.[1]
Prognosis
The fiver year survival for patients starting both hemodialysis and peritoneal dialysis is about 35%.[1]
References
- ↑ 1.0 1.1 1.2 1.3 1.4 1.5 Meyer TW, Hostetter TH (2007). "Uremia". N. Engl. J. Med. 357 (13): 1316–25. DOI:10.1056/NEJMra071313. PMID 17898101. Research Blogging.