Cirrhosis

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Cirrhosis is a "liver disease in which the normal microcirculation, the gross vascular anatomy, and the hepatic architecture have been variably destroyed and altered with fibrous septa surrounding regenerated or regenerating parenchymal nodules."[1]

Complications

Ascites

For more information, see: Ascites.


Esophageal varices

Patients with a platelet count of less than 40 and a palpable spleen are more likely to have esophageal varices.[2]

Hepatic encephalopathy

For more information, see: Hepatic encephalopathy.


Hepatorenal syndrome

For more information, see: Hepatorenal syndrome.


Prognosis

MELD Score

For more information, see: MELD Score.

The MELD Score can help predict mortality. An online calculator is available.

References

  1. ↑ Anonymous. Liver cirrhosis. National Library of Medicine. Retrieved on 2008-01-07.
  2. ↑ Sharma SK, Aggarwal R (2007). "Prediction of large esophageal varices in patients with cirrhosis of the liver using clinical, laboratory and imaging parameters". J. Gastroenterol. Hepatol. 22 (11): 1909–15. DOI:10.1111/j.1440-1746.2006.04501.x. PMID 17914969. Research Blogging.
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