Photon absorptiometry

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In medicine, photon absorptiometry is a "noninvasive method for assessing body composition. It is based on the differential absorption of x-rays (or gamma rays) by different tissues such as bone, fat and other soft tissues. The source of (x-ray or gamma ray) photon beam is generated either from radioisotopes such as 153gadolinium, 126iodine 125, or 241americium which emit gamma rays in the appropriate range; or from an x-ray tube which produces x-rays in the desired range. It is primarily used for quantitating bone mineral content, especially for the diagnosis of osteoporosis, and also in measuring bone mineralization."[1]

Method Source Detection levels
Single-photon absorptiometry (SPA) Isotope Single
Dual-photon absorptiometry (DPA) Isotope Dual
Dual-Energy X-Ray Absorptiometry (DEXA) X-ray Dual


Measurement of bone density

For more information, see: Bone densitometry.


Bone density is generally scored by two measures, the T-score and the Z-score. Scores indicate the amount one's bone mineral density varies from the mean. Negative scores indicate lower bone density, and positive scores indicate higher.

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