Healthy obesity

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Revision as of 12:13, 31 October 2011 by imported>Liam Jon Carr
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What is Healthy Obesity?

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This article is currently being developed as part of an Eduzendium student project in the framework of a course entitled Appetite and Obesity at Edinburgh University. The course homepage can be found at CZ:UoE Appetite and Obesity 2011.
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Although obesity is a major risk factor for cardiovascular disease and type 2 diabetes mellitus, about a third of obese individuals maintain healthy cardiometabolic profiles; this phenotype of healthy obesity may be linked to the location of adipose tissue and the metabolic characteristics of the fat. Some data also suggest that weight loss by healthy obese subjects may have an adverse impact on their favorable cardiometabolic profile. [1] [2]


Why is Healthy Obesity Worthwhile investigating?

The Cause of Healthy Obesity?

Criticism of Current Data - Does the Healthy Obesity Phenotype Actually Exist?

Evidence for the existence of the healthy obese category:

Conflicting findings of meta-analyses from NEJM and American heart journal etc. the impact of adjusting for physical activity and the role of other parameters. eg. lack of any the metabolic syndrome criteria & no insulin resistance counts as healthy. non metabolic morbidity.

or if that overlaps too much with someone else's section I could cover:

the role of ethnicity: A higher proportion of black healthy obese? Possible underlying mechanism?

Losing weight can be harmful for the healthy obese: (Gaesser 1999)Tijmen van Slageren 18:38, 24 October 2011 (UTC)









References

  1. Lee CM et al. (2008) Indices of abdominal obesity are better discriminators of cardiovascular risk factors than BMI: a meta-analysis J Clin Epidemiol 61:646-53 PMID 18359190
  2. Wildman RP (2009) Healthy obesity Curr Opin Clin Nutr Metab Care 12:438-43 PMID 19474713