Major depressive disorder

Depression Diagnosis and classification of Depressive disorder The core symptoms of depression are depressed mood and a lack of interest or pleasure from daily activities (anhedonia). Several additional features may be present, like lack of concentration, inappropriate guilt feelings, suicidal thoughts, psychomotor retardation or agitation and loss of libido. A diurnal variation, e.g. the symptoms are worse in the morning, may be present. In Psychiatry a diagnosis is made with the use of a classification system. The newest version of this classifiaction system is the Diagnostic and Statistical Manual of Mental Disorders (fourth version, DSM-IV).