Headache

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Headache is defined as the symptom of pain in the cranial region. It may be an isolated benign occurrence or manifestation of a wide variety of headache disorders.[1]

Classification

Primary headaches

Primary headaches are defined as "conditions in which the primary symptom is headache and the headache cannot be attributed to any known causes."[1]

Migraine headache

For more information, see: Migraine headache.
Criteria

Diagnostic criteria developed by the International Headache Society are:[2]
Migraine without aura:
A. At least 5 attacks fulfilling criteria B-D
B. Headache attacks lasting 4-72 hours (untreated or unsuccessfully treated)
C. Headache has at least two of the following characteristics:

  1. unilateral location
  2. pulsating quality
  3. moderate or severe pain intensity
  4. aggravation by or causing avoidance of routine physical activity (eg, walking or climbing stairs)

D. During headache at least one of the following:

  1. nausea and/or vomiting
  2. photophobia and phonophobia

E. Not attributed to another disorder

Tension headache

For more information, see: Tension headache.


Cluster headache

Criteria

Diagnostic criteria developed by the International Headache Society are:[3]
A. At least 5 attacks fulfilling criteria B-D
B. Severe or very severe unilateral orbital, supraorbital and/or temporal pain lasting 15-180 minutes if untreated1
C. Headache is accompanied by at least one of the following:

  1. ipsilateral conjunctival injection and/or lacrimation
  2. ipsilateral nasal congestion and/or rhinorrhoea
  3. ipsilateral eyelid oedema
  4. ipsilateral forehead and facial sweating
  5. ipsilateral miosis and/or ptosis
  6. a sense of restlessness or agitation

D. Attacks have a frequency from one every other day to 8 per day
E. Not attributed to another disorder

Secondary headache

Secondary headaches are defined as "conditions with headache symptom that can be attributed to a variety of causes including brain vascular disorders; wounds and injuries; infection; drug use or its withdrawal."[1]

The role of overuse of medications for treating migraine (triptans, analgesics, ergots) and their withdrawal as a cause of headache is controversial.[4]

Diagnosis

X-ray computed tomography (CT Scan) should be considered if one of the following is present:[5]

  • cluster-type headache
  • abnormal findings on neurologic examination
  • undefined headache (ie, not cluster, migraine, or tension-type)
  • headache with aura
  • headache aggravated by exertion or a valsalva-like maneuver
  • headache with vomiting

CT scan should also be considered in the following settings:

  • Acute thunderclap headache. Prevalence of significant pathology is 40%[5]
  • New-onset or change in chronic headaches. Prevalence of significant pathology is 32%.[5] This compares to a prevalence of significant pathology of 1% for patients with chronic headaches referred to a neurologist.[6] Presumably the prevalence would be lower in primary care.
  • Patients with human immunodeficiency virus. This is based on a clinical practice guideline.[7]

Treatment

Prochlorperazine is better than promethazine in relieving nonspecific, benign headaches according to a randomized controlled trial.[8]

Migraine headache

For more information, see: Migraine headache.


Tension headache

For more information, see: Tension headache.


Prognosis

Most chronic headaches are tension-type headache, although migraine may coexist.[9] Almost half have medication overuse.[9]

References

  1. 1.0 1.1 1.2 National Library of Medicine. Headache. Retrieved on 2007-12-11. Cite error: Invalid <ref> tag; name "title" defined multiple times with different content Cite error: Invalid <ref> tag; name "title" defined multiple times with different content
  2. International Headache Society. Migraine headache
  3. International Headache Society. Cluster headache
  4. Bøe MG, Mygland A, Salvesen R (2007). "Prednisolone does not reduce withdrawal headache: a randomized, double-blind study". Neurology 69 (1): 26–31. DOI:10.1212/01.wnl.0000263652.46222.e8. PMID 17475943. Research Blogging.
  5. 5.0 5.1 5.2 Detsky ME, McDonald DR, Baerlocher MO, Tomlinson GA, McCrory DC, Booth CM (2006). "Does this patient with headache have a migraine or need neuroimaging?". JAMA 296 (10): 1274–83. DOI:10.1001/jama.296.10.1274. PMID 16968852. Research Blogging.
  6. Sempere AP, Porta-Etessam J, Medrano V, et al (2005). "Neuroimaging in the evaluation of patients with non-acute headache". Cephalalgia 25 (1): 30–5. DOI:10.1111/j.1468-2982.2004.00798.x. PMID 15606567. Research Blogging.
  7. (2002) "Clinical policy: critical issues in the evaluation and management of patients presenting to the emergency department with acute headache". Ann Emerg Med 39 (1): 108–22. PMID 11782746[e]
  8. Callan JE, Kostic MA, Bachrach EA, Rieg TS (October 2008). "Prochlorperazine vs. promethazine for headache treatment in the emergency department: a randomized controlled trial". J Emerg Med 35 (3): 247–53. DOI:10.1016/j.jemermed.2007.09.047. PMID 18534808. Research Blogging.
  9. 9.0 9.1 Grande RB, Aaseth K, Saltyte Benth J, Gulbrandsen P, Russell MB, Lundqvist C (July 2009). "The Severity of Dependence Scale detects people with medication overuse: the Akershus study of chronic headache". J. Neurol. Neurosurg. Psychiatr. 80 (7): 784–9. DOI:10.1136/jnnp.2008.168864. PMID 19279030. Research Blogging.