Methotrexate

(CC) Image: David E. Volk
Structure of Methotrexate.

(CC) Image: David E. Volk
Folic acid.

Methotrexate (MTX) is a drug used in the treatment of a variety of cancers, and autoimmune disorders such as asthma and rheumatoid arthritis. It is a nucleic acid anti-metabolite (like 6-MP), and a folic acid antagonist due to its similarity in structure.

common synonyms

• Mexate
• Methylaminopterin
• Emtexate
• Metatrexan
• Methopterin
• MTX dihydrate
• Folex
• Folex PFS
• Amethopetrin

External links

The most up-to-date information about Methotrexate and other drugs can be found at the following sites.

• Methotrexate - FDA approved drug information (drug label) from DailyMed (U.S. National Library of Medicine).
• Methotrexate - Drug information for consumers from MedlinePlus (U.S. National Library of Medicine).
• Methotrexate - Detailed information from DrugBank.