Carotid endarterectomy

From Citizendium
Revision as of 13:17, 6 January 2009 by imported>Robert Badgett (→‎Preoperative assessment)
Jump to navigation Jump to search

In medicine, carotid endarterectomy, or CEA, is "excision of the thickened, atheromatous tunica intima of a carotid artery."[1] This is done to prevent a stroke.

Concomitant aspirin may decrease complications.[2][3]

Effectiveness

CEA can benefit patients with[4] and without[5] symptoms according to systematic reviews by the Cochrane Collaboration and the American Academy of Neurology[3].

Preoperative assessment

The preoperative care includes assessment for coronary heart disease. In one study, 40% of patients had coronary heart disease, with 18% of the patients (or 48% of those with coronary heart disease) had severe disease (obstruction of the left main or three of the arteries).[6] The strongest predictor of coronary heart disease was the presence of diabetes mellitus. The presence of bilateral carotid disease was not a significant prediction of coronary disease. The presence of cardiac symptoms probably increasess the likelihood of coronary disease.[7]

The role of coronary angiography[8] and coronary revascularization[9] are not established.

References

  1. Anonymous (2024), Carotid endarterectomy (English). Medical Subject Headings. U.S. National Library of Medicine.
  2. Taylor DW, Barnett HJ, Haynes RB, et al (June 1999). "Low-dose and high-dose acetylsalicylic acid for patients undergoing carotid endarterectomy: a randomised controlled trial. ASA and Carotid Endarterectomy (ACE) Trial Collaborators". Lancet 353 (9171): 2179–84. PMID 10392981[e]
  3. 3.0 3.1 Chaturvedi S, Bruno A, Feasby T, et al (September 2005). "Carotid endarterectomy--an evidence-based review: report of the Therapeutics and Technology Assessment Subcommittee of the American Academy of Neurology". Neurology 65 (6): 794–801. DOI:10.1212/01.wnl.0000176036.07558.82. PMID 16186516. Research Blogging.
  4. Cina CS, Clase CM, Haynes RB (2000). "Carotid endarterectomy for symptomatic carotid stenosis". Cochrane Database Syst Rev (2): CD001081. DOI:10.1002/14651858.CD001081. PMID 10796411. Research Blogging.
  5. Chambers BR, Donnan GA (2005). "Carotid endarterectomy for asymptomatic carotid stenosis". Cochrane Database Syst Rev (4): CD001923. DOI:10.1002/14651858.CD001923.pub2. PMID 16235289. Research Blogging.
  6. Shimada T, Toyoda K, Inoue T, et al (October 2005). "Prediction of coronary artery disease in patients undergoing carotid endarterectomy". J. Neurosurg. 103 (4): 593–6. PMID 16266039[e]
  7. Chimowitz MI, Weiss DG, Cohen SL, Starling MR, Hobson RW (April 1994). "Cardiac prognosis of patients with carotid stenosis and no history of coronary artery disease. Veterans Affairs Cooperative Study Group 167". Stroke 25 (4): 759–65. PMID 8160217[e]
  8. Massie MT, Rohrer MJ, Leppo JA, Cutler BS (June 1997). "Is coronary angiography necessary for vascular surgery patients who have positive results of dipyridamole thallium scans?". J. Vasc. Surg. 25 (6): 975–82; discussion 982–3. PMID 9201157[e]
  9. McFalls EO, Ward HB, Moritz TE, et al (December 2004). "Coronary-artery revascularization before elective major vascular surgery". N. Engl. J. Med. 351 (27): 2795–804. DOI:10.1056/NEJMoa041905. PMID 15625331. Research Blogging.