Folic acid/Related Articles
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- See also changes related to Folic acid, or pages that link to Folic acid or to this page or whose text contains "Folic acid".
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- Tetrahydrofolate dehydrogenase [r]: An enzyme of the oxidoreductase class that catalyzes the reaction 7,8-dihydrofolate and NADPH to yield 5,6,7,8-tetrahydrofolate and NADPH+, producing reduced folate for amino acid metabolism, purine ring synthesis, and the formation of deoxythymidine monophosphate. Methotrexate and other folic acid antagonists used as chemotherapeutic drugs act by inhibiting this enzyme. Also known as dihydrofolate dehydrogenase, dihydrofolate reductase and folic acid reductase; differs from methylenetetrahydrofolate reductase [e]
- Tetrahydrofolate dehydrogenase inhibitors [r]: Add brief definition or description
- Methotrexate [r]: An inhibitor of tetrahydrofolate dehydrogenase, which prevents the formation of tetrahydrofolate, necessary for synthesis of thymidylate, an essential component of DNA; it has a wide range of medical applications. [e]
- Sulfamethoxazole [r]: A sulfonamide antibacterial agent that interferes with folic acid synthesis in susceptible bacteria. Its broad spectrum of activity has been limited by the development of resistance, but it is more effective as the Trimethoprim-Sulfamethoxazole combination [e]
- Atovaquone-proguanil [r]: Fixed-combination antimalarial that may have action against babesiosis; approved for chloroquine-resistant Plasmodium falciparum [e]
- Tetrahydrofolate dehydrogenase inhibitors [r]: Add brief definition or description
- Anemia [r]: A condition characterized by insufficient circulating and effective hemoglobin in blood to support normal physiology. [e]
- Antibiotic [r]: Drugs that reduce the growth or reproduction of bacteria. [e]
- Antineoplastic agent [r]: Drug that prevents the development, maturation, or spread of neoplastic cells. [e]
- Dietary supplement [r]: Preparation intended to provide nutrients, such as vitamins, minerals, fiber, fatty acids or amino acids, that are missing or are not consumed in sufficient quantity in a person's diet. [e]
- Thalassemia [r]: A group of hereditary hemolytic anemias in which there is decreased synthesis of one or more hemoglobin polypeptide chains (National Library of Medicine). [e]
- Vascular disease [r]: Pathological processes involving any of the blood vessels in the cardiac or peripheral circulation. They include diseases of arteries; veins; and rest of the vasculature system in the body. [e]