Cervical cancer
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Screening
In a randomized controlled trial, the addition of Human papillomavirus testing to screenng for cervical cancer "reduces the incidence of grade 2 or 3 cervical intraepithelial neoplasia or cancer detected by subsequent screening examinations."[1]
Papanicolaou smear
Conventional method
- sensitivity 55%[1]
- specificity 94%[1]
Liquid-based thin prep
Liquid-based thin prep is more sensitive than the conventional Papanicolaou smear.
Human papillomavirus testing
- sensitivity 95%[1]
- specificity 97%[1]
Combined testing
If either the Papanicolaou smear or Human papillomavirus testing are abnormal:
- sensitivity 100%[1]
- specificity 93%[1]