Warfarin

(CC) Image: David E. Volk
Structure of Warfarin.

Warfarin (IUPAC name 4-hydroxy-3-(3-oxo-1-phenylbutyl)-2H-chromen-2-one), also widely called coumadin, is a an anticoagulant medication used prophylactically to suppress the formation of thrombosis and embolism. It was originally designed to be a rat poison. It works as an anticogulant by suppressing the enzyme epoxide reductase in the liver, thereby suppresing the formation of the reduced form of vitamine K epoxide, which is needed for the synthesis of many coagulation factors. As a drug, it is often sold as the sodium salt of warfarin.

Brand names

• Athrombin
• Athrombin-K
• Athrombine-K
• Brumolin
• Co-Rax
• Coumadin
• Coumafen
• Coumafene
• Coumaphen
• Coumaphene
• Coumarins
• Coumefene
• D-Con
• Dethmor
• Dethnel
• Dicusat E
• Frass-Ratron
• Jantoven
• Kumader
• Kumadu
• Kumatox
• Kypfarin
• Latka 42
• Mar-Frin
• Marevan
• Maveran
• Panwarfin
• Place-Pax
• Prothromadin
• RAX
• Rosex
• Sofarin
• Solfarin
• Sorexa Plus
• Temus W
• Tintorane
• Tox-Hid
• Vampirinip II
• Vampirinip III
• Waran
• Warf 42
• Warfarat
• Warfarin Plus
• Warfarin Q
• Warfarine
• Warficide
• Warfilone
• Zoocoumarin

External links

• Warfarin - FDA approved drug information (drug label) from DailyMed (U.S. National Library of Medicine).