Coagulase/Related Articles

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Coagulase: Enzymes that cause coagulation in plasma by forming a complex with human prothrombin, and produced by certain bacteria including Staphylococcus species and Yersinia pestis. Staphylococci produce two types of coagulase: Staphylocoagulase, a free coagulase that produces true clotting of plasma, and Staphylococcal clumping factor, a bound coagulase in the cell wall that induces clumping of cells in the presence of fibrinogen. [e]

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  • Staphylococcus aureus [r]: Facultatively anaerobic, Gram-positive pathogenic coccus capable of producing suppurative lesions, furunculosis, pyemia, osteomyelitis, food poisoning, and may be resistant to commonly used antibiotics. [e]

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