Nocturnal leg cramps

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In medicine, nocturnal leg cramps are a sleep-wake transition disorder which is a type of parasomia.[1]

Various medications may cause nocturnal leg cramps:[2]

Treatment

Clinical practice guidelines direct treatment. Quinine should be avoided.[3] However, some patients probably benefit from quinine.[4]

Muscle stretching may help.[5]

References

  1. Anonymous (2024), Sleep-wake transition disorders (English). Medical Subject Headings. U.S. National Library of Medicine.
  2. Garrison, Scott R.; Colin R. Dormuth, Richard L. Morrow, Greg A. Carney, Karim M. Khan (2011-12-12). "Nocturnal Leg Cramps and Prescription Use That Precedes Them: A Sequence Symmetry Analysis". Arch Intern Med: archinternmed.2011.1029. DOI:10.1001/archinternmed.2011.1029. Retrieved on 2011-12-13. Research Blogging.
  3. Katzberg, Hans D.; Ahmir H. Khan, Yuen T. So (2010-02-23). "Assessment: Symptomatic treatment for muscle cramps (an evidence-based review): Report of the Therapeutics and Technology Assessment Subcommittee of the American Academy of Neurology". Neurology 74 (8): 691-696. DOI:10.1212/WNL.0b013e3181d0ccca. PMID 20177124. Retrieved on 2010-02-23. Research Blogging.
  4. Woodfield R, Goodyear-Smith F, Arroll B (2005). "N-of-1 trials of quinine efficacy in skeletal muscle cramps of the leg.". Br J Gen Pract 55 (512): 181-5. PMID 15808032. PMC PMC1463087.
  5. Hallegraeff JM, van der Schans CP, de Ruiter R, de Greef MH (2012). "Stretching before sleep reduces the frequency and severity of nocturnal leg cramps in older adults: a randomised trial.". J Physiother 58 (1): 17-22. DOI:10.1016/S1836-9553(12)70068-1. PMID 22341378. Research Blogging.